PhysicalTherapy.com Phone: 866-782-6258


Shockwave Therapy: Mechanisms, Pain Reduction, and Treatment Types

Mark Callanen, PT, DPT, OCS

June 1, 2025

Share:

Question

How does shockwave therapy work, and what are the differences between radial and focused shockwave therapy?

Answer

Shockwave therapy is a non-invasive treatment that uses high-energy sound waves to promote healing and reduce pain in musculoskeletal tissues. It works through two primary mechanisms: mechanotransduction, which converts mechanical forces into biochemical signals that stimulate blood flow, collagen production, and tissue regeneration, and cavitation, which involves the formation and collapse of microbubbles within the tissue, enhancing cellular activity and accelerating the healing process.

Shockwave therapy also reduces pain through neural desensitization and the modulation of pain-signaling neurotransmitters like substance P. The rapid pulses create a temporary noxious stimulus, leading to a depletion of substance P and activation of descending inhibitory pain pathways, which reduces discomfort. This combination of healing and pain relief makes shockwave therapy particularly effective for chronic tendinopathies, plantar fasciitis, and myofascial pain.

Two primary types of shockwave therapy exist: focused shockwave therapy (FSW) and radial pressure wave (RPW) therapy. Focused shockwave therapy generates a high-intensity wave that reaches peak energy at a specific depth below the skin, making it ideal for treating deep tissue conditions such as calcific tendinopathy. In contrast, RPW therapy produces a more diffuse energy that is strongest at the skin’s surface and gradually dissipates as it penetrates, making it well-suited for treating superficial conditions like myofascial trigger points. Despite these differences, research indicates that both modalities yield similar clinical outcomes for musculoskeletal conditions when dosed appropriately.

This Ask the Expert is an edited excerpt from the course "An Overview of Shockwave Technologies: Treatment Guidelines, Indications, and Contraindications," presented by Mark Callanen, PT, DPT, OCS.


mark callanen

Mark Callanen, PT, DPT, OCS

Prior to joining Enovis’ ™ marketing and clinical education team, Dr. Callanen treated orthopedic patients and managed therapists in an outpatient setting for 18 years.  He has been board certified as an Orthopedic Clinical Specialist (OCS) by the APTA since 2003. He graduated with his transitional Doctorate in Physical Therapy in 2007 from Marymount University in Arlington, VA, after earning his Master of Physical Therapy from Shenandoah University in 1999.   

Dr. Callanen acquired his therapeutic laser acumen after joining LiteCure, LLC and the LightForce® team in early 2017 while serving as their Director of Clinical Development.  LiteCure, LLC was acquired by DJO, LLC in December 2020.  DJO’s parent company, Colfax Corporation, has rebranded as Enovis™, where Dr. Callanen is currently serving as the Director of US Marketing and Clinical Education for the Enovis™ Recovery Sciences Division.  He has made formal presentations on laser therapy to mixed professional audiences nationally and internationally and began lecturing on shockwave therapies in 2021.  Dr. Callanen is also an Adjunct Professor for Belmont University’s Physical Therapy Program in Nashville, TN.  


Related Courses

Laser Therapy: Review of Photobiomodulation and Dosing for Specific Conditions, in partnership with Enovis™
Presented by Mark Callanen, PT, DPT, OCS
Recorded Webinar

Presenter

Mark Callanen, PT, DPT, OCS
Course: #4863Level: Intermediate2.5 Hours
  'good and useable content'   Read Reviews
This course is designed to provide a well-rounded overview of light-based therapy and factors that influence photobiomodulation (PBM). Specific subject matter includes a reference-based review of how light interacts with tissue and impacts different pathologies, as well as dosing concepts for different clinical applications.

An Overview of Shockwave Technologies: Treatment Guidelines, Indications, and Contraindications, in partnership with Enovis™
Presented by Mark Callanen, PT, DPT, OCS
Recorded Webinar

Presenter

Mark Callanen, PT, DPT, OCS
Course: #5147Level: Intermediate2 Hours
  'Comprehensive and able to implement effective treatment immediately'   Read Reviews
This course provides an overview of shockwave technologies, differentiating and comparing focused shockwave and radial pressure wave technologies. It covers evidence-based treatment recommendations along with general indications and contraindications.

Application of Pain Science: An Introduction
Presented by Adam Strizak, PT, DPT, OCS
Recorded Webinar

Presenter

Adam Strizak, PT, DPT, OCS
Course: #3923Level: Introductory2 Hours
  'Very interesting way to look at chronic pain and a different approach to treatment that I have never seen'   Read Reviews
Pain neuroscience education consists of educational sessions for patients describing in detail the neurobiology and neurophysiology of pain and pain processing by the nervous system. Through Pain Neuroscience Education patients have been found to have a reduction in fear avoidance behaviors and are more able and willing to move. This course is an introduction to Pain Neuroscience Education and the basics to get you started. This course is directly related to the practice of physical therapy and athletic training and is therefore appropriate for the PT/PTA and AT.

Sports Psychology for the Aging Athlete: The Mind Body Connection
Presented by Daniel Schweigert, MD
Recorded Webinar

Presenter

Daniel Schweigert, MD
Course: #3800Level: Intermediate2 Hours
  'Great topic with very thorough review - applicable not just to athletes, but to general patient population as well'   Read Reviews
This course is designed for physical therapists, athletic trainers, coaches, and athletes to more fully understand the limits of peak athletic performance of the aging body, how accumulated trauma, stress, and anxiety contribute to athletic decline and what can be done to slow the rate of decline and enhance performance as the athlete ages. This course is directly related to the practice of physical therapy and athletic training and is therefore appropriate for the PT/PTA and AT.

Complex and Chronic Impairment in Concussion
Presented by Laura Morris, PT, NCS
Recorded Webinar

Presenter

Laura Morris, PT, NCS
Course: #4353Level: Intermediate2 Hours
  'I was a pedestrian hit by a car this year and sustained a TBI'   Read Reviews
This webinar will include an exploration of the various etiologies of dysfunction following mTBI, including, headache, visual/oculomotor impairment, chronic dizziness, and pain. The challenging issue of prioritizing intervention and appropriate referral to other medical practitioners will be discussed. This course is directly related to the practice of physical therapy and athletic training and is therefore appropriate for the PT/PTA and AT.

Our site uses cookies to improve your experience. By using our site, you agree to our Privacy Policy.