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Medication Side Effect: Confusion

Kenneth L. Miller, PT, DPT, GCS, CEEAA

November 4, 2015

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Question

Do medications cause confusion at times and if so which ones are able to do so?  

Answer

As therapists, we need to start looking at the medications and their side effects to see if they are possibly having confusion side effects.  This may be the problem the patient is having all along.   Antidepressants cause confusion.  Opioid analgesics cause confusion.  Drugs with anticholinergic effects also cause confusion.  Certain medications become toxic in the blood.  They have a very long half-life and they have to be monitored with blood work to make sure that the medicine is not going to a toxic level.  Two medications in particular that cause problems related to toxicity are lithium and digoxin.  This is one reason why you see these medicines being prescribed less often than they used to be.  As far as lithium goes, they have other antipsychotic medications that do not have the same toxicity.  Digoxin is a heart pill and it is prescribed less than it used to be, because we are catching heart failure at an earlier stage and therefore is able to be treated with diuretics.  Worsening of confusion for people with mild cognitive impairment can also occur with specific medications.  Be aware of this as you are treating your patients.  See what they are taking, and if you are not sure if what they are taking is causing this, I recommend downloading a free app called WebMD to put on your iPhone or android device.  With this app, you can look up any medication and it will tell you the indications for use, all the side effects, and it will have pictures of the medications inorder to determine generic pills over name brands.  


kenneth l miller

Kenneth L. Miller, PT, DPT, GCS, CEEAA

Dr. Kenneth L. Miller is a board-certified geriatric clinical specialist, advanced credentialed exercise expert for aging adults, and credentialed clinical instructor from the APTA. He has over 26 years of clinical experience with the older adult population.  Dr. Miller is an assistant professor at the University of North Texas Science Center with dual appointments in the Department of Physical Therapy in the School of Health Professions and in the Department of Internal Medicine and Geriatrics in the Texas College of Osteopathic Medicine. 

His clinical focus is on best practices for use with the older adult population.  He has spoken nationally and internationally on topics of gerontology including primary prevention, fragility, outcome measures, and pharmacology. 

He serves on editorial boards related to geriatric care and physical therapy education including Topics in Geriatric Rehabilitation where he was guest editor for a thematic issue dedicated to pharmacology and nutrition.  He also serves the physical therapy profession as director of practice for the Academy of Geriatric Physical Therapy and on several Academy Task Forces.  Most recently, he has helped to develop the best practice guidelines for the Academy that describe best practices for the care of older adults.  Dr. Miller is also a co-editor of the Ciccone's Pharmacology in Rehabilitation 5th edition textbook update.  

 


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