What factors may contribute to a poorer outcome in people with Guillain-Barre Syndrome?
Answer
According to research, the following factors may contribute to a poorer outcome:
If the patient is older at age of onset
If the patient requires respiratory support and further dependence for breathing
If the patient experiences abnormal peripheral nerve function
If the patient was not given plasma or IV immunoglobin therapy; no plasmapheresis
If the patient has a variant of GBS with primary axonal degeneration; regeneration of the axon and myelin sheath takes twice as much work
If there is a progression to quadriplegia
If the disease was severe at presentation
If one of the causing factors was the Campylobacter jejuni infection in the small intestines (causes diarrhea)
Jennifaye V. Brown, PT, MSPT, PhD, NCS, CAPS
Jennifaye V. Brown, PT, MSPT, PhD, NCS, CAPS has 35 years of clinical experience focused in neurorehabilitation across the continuum of care and has presented numerous continuing education courses on adult neurologic assessment and treatment intervention for acquired brain injury, particularly stroke. Her primary research explored the perceptions of individuals with stroke regarding their experiences with AFO fabrication, modification, and maintenance, and how the AFO impacts walking and participation in life roles, resulting in the book, Brace Yourself - Everything You Need to Know About AFOs After Stroke. She is an NDT-trained therapist with six additional courses taken after the NDT (Bobath) Three Week Course on Treatment of Adult Hemiplegia course. As an Advanced Credentialed Clinical Instructor by the Clinical Instructor Education Board and a four 10-year term board-certified neurologic clinical specialist by the American Board of Physical Therapy Specialties (ABPTS) of the APTA, Dr. Brown has taught at six PT and two PTA programs. She is a Certified Aging in Place Specialist, a member of the APTA, Neurology Section of the APTA, SC Chapter of the APTA, and Athletics & Fitness Association of America, and a graduate of the prestigious APTA Fellowship in Education Leadership.
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